" /> EWSR1-SMAD3 Rearranged Fibroblastic Tumor - CISMeF





Preferred Label : EWSR1-SMAD3 Rearranged Fibroblastic Tumor;

NCIt synonyms : EWSR1::SMAD3 Rearranged Fibroblastic Tumor; EWSR1::SMAD3-Positive Fibroblastic Tumor; EWSR1-SMAD3-Positive Fibroblastic Tumor;

NCIt definition : A benign fibroblastic neoplasm characterized by a fusion of exon 7 of EWSR1 gene with exon 5 of SMAD3 gene. Patients usually present with a small painless superficial tumor in the hands and feet. Morphologically, there is zonation with acellular hyalinized center and peripheral proliferation of fibroblastic spindle cells without atypia. It may recur following incomplete excision.;

Neoplastic status : Benign;

Concept status : Provisional_Concept;

NCI Metathesaurus CUI : CL1643046;

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16/08/2025


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