Preferred Label : Eclitasertib;
NCIt definition : An orally bioavailable, small-molecule inhibitor of receptor-interacting serine/threonine-protein
kinase 1 (RIPK1; receptor-interacting protein 1; RIP1), with potential anti-inflammatory
and immunomodulatory activities. Upon oral administration, eclitasertib disrupts RIPK1-mediated
signaling, and may attenuate inflammation and the resulting tissue damage. RIPK1,
a signaling protein in the tumor necrosis factor (TNF) receptor pathway, plays a key
role in inflammation and cell death in response to tissue damage and pathogen recognition.;
UNII : 975AT1P9J6;
InChIKey : XUZICJHIIJCKQQ-ZDUSSCGKSA-N;
CAS number : 2125450-76-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2125450-76-0
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : SAR-443122; DNL-758; SAR 443122; DNL 758;
NCI Metathesaurus CUI : CL1642851;
Origin ID : C177073;
UMLS CUI : C5447567;
Semantic type(s)
- concept_is_in_subset
