NCIt definition : A neutralizing human monoclonal antibody isolated from convalescent patients with
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and directed
against the spike (S) protein, that can potentially be used for passive immunization
against Coronavirus disease 2019 (COVID-19). Upon administration, cilgavimab specifically
targets and binds to the SARS-CoV-2 S protein, thereby blocking viral attachment and
entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression
of the disease and accelerate recovery, and may potentially provide temporary protection
against infection with SARS-CoV-2. S protein, usually found on the surface of SARS-CoV-2,
plays an essential role in the infection pathway of the SARS-CoV-2 virus.;
UNII : 1KUR4BN70F;
CAS number : 2420563-99-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2420563-99-9
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