" /> Goflikicept - CISMeF





Preferred Label : Goflikicept;

NCIt definition : A heterodimeric fusion protein comprised of the extracellular portions of human interleukin (IL)-1 receptor type 1 (IL-1R1) and IL-1 receptor accessory protein (IL-1RAcP) linked to a mutant Fc portion of human immunoglobulin G1 (IgG1), with potential anti-inflammatory activity. Upon administration, goflikicept targets and binds to the proinflammatory cytokine IL-1 beta (IL-1b) and prevents the binding of IL-1b to the IL-1 receptor. This inhibits IL-1b-mediated signaling pathways, and suppresses inflammatory responses mediated by IL-1b. IL-1b plays a key role in inflammation, which is present in various disease states.;

UNII : 11DRN01OK2;

CAS number : 2416984-26-2;

Molecule name : RPH 104; RPH-104;

NCI Metathesaurus CUI : CL1642839;

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Keyword's position in hierarchy(ies) : arborescence

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04/05/2025


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