Preferred Label : Chocolate-based Dietary Supplement;
NCIt definition : A dietary supplement containing chocolate derived from the cacao bean, with potential
vasodilating, anti-inflammatory, antioxidant, cardiovascular protective and neuroprotective
activities. Chocolate contains flavonoids, including epicatechin, catechin, procyanidins
and xanthines, such as theobromine, and trace minerals. Upon oral administration,
the bioactive ingredients in the chocolate-based dietary supplement may inhibit angiotensin-converting
enzyme (ACE) and increase the production of nitric oxide (NO) through the activation
of endothelial nitric oxide synthase (eNOS). This may result in vasodilation, improve
blood flow, and decrease blood pressure. The chocolate-based dietary supplement also
may improve insulin sensitivity, enhance cognition, and decrease the production of
pro-inflammatory molecules. In addition, chocolate-based dietary may exert antioxidant
effects and scavenge reactive oxygen species (ROS), thereby protecting cells from
oxidative stress and DNA damage.;
NCI Metathesaurus CUI : CL1642926;
Origin ID : C176869;
UMLS CUI : C5447483;
Semantic type(s)
- concept_is_in_subset
