Degradant - CISMeF

Preferred Label : Degradant;

NCIt related terms : Degradation Product;

NCIt definition : An impurity resulting from a chemical change in the drug substance.;

Alternative definition : PQCMC: A molecule resulting from a chemical change brought about over time and/or by the action of something (e.g., light, temperature, pH, water, or by reaction with an excipient and/or the immediate container/closure system). [Source: SME Defined];

NCI Metathesaurus CUI : CL1642627;

Details

Origin ID

C176816;

UMLS CUI

C5447451;

Automatic exact mappings (from CISMeF team)
- Degradation [PASCAL theme]
- Degraded [ICD-11 Extension code]
- catabolic process [GO term]
- metabolism [MeSH Qualifier]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Pharmaceutical Quality/CMC Terminology [NCIt concept]
- PQ/CMC Impurity Classification Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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