Preferred Label : TLR7 Agonist RO7119929;
NCIt definition : An orally bioavailable Toll-like receptor (TLR) 7 agonist, with potential immunostimulating
and antitumor activities. Upon oral administration, TLR7 agonist RO7119929 targets,
binds to and activates TLR7. This may trigger the activation of cluster of differentiation
(CD) 8-positive T cells, B cells, and innate immune cells including natural killer
(NK) cells and macrophages, and may induce the production of cytokines including interferon
alpha (IFNa), leading to antitumor activity. TLR7 is a member of the TLR family, which
plays a fundamental role in pathogen recognition and activation of innate immunity.;
Molecule name : RO 7119929; RO-7119929;
NCI Metathesaurus CUI : CL1642589;
Origin ID : C176749;
UMLS CUI : C5447413;
Semantic type(s)
- concept_is_in_subset
