Preferred Label : Experimental Organism Amphophilic Vacuolar Carcinoma;
NCIt related terms : CARCINOMA, AMPHOPHILIC VACUOLAR, MALIGNANT;
NCIt definition : A carcinoma that arises from the renal tubules in rats. It is characterized by the
presence of malignant large, round to polyhedral finely granular cells with amphophilic
to eosinophilic cytoplasm, numerous vacuoles, and prominent nucleoli.;
Alternative definition : CDISC: A malignant neoplasm of the renal tubules, composed of distinct lobules of
large, round to polyhedral cells with vacuolated amphophilic to eosinophilic cytoplasm
and prominent nucleoli. (Crabbs TA, Frame SR, Laast VA, Patrick DJ, Thomas J, Zimmerman
B, Hardisty JF (2013) Occurrence of spontaneous amphophilic-vacuolar renal tubule
tumors in Sprague-Dawley rats from subchronic toxicity studies. Toxicol Pathol 41:866-87);
NCI Metathesaurus CUI : CL1642458;
Origin ID : C176393;
UMLS CUI : C5447224;
Semantic type(s)
- concept_is_in_subset
