Tumor Progression

Preferred Label : Tumor Progression;

NCIt related terms : Progression;

NCIt definition : A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm.;

NCIt note : The process of tumor progression is thought to be driven by clonal evolution. The initiating event is a mutation that gives a cell the ability to divide when it shouldn't. As a result a small group of related cells, called a clone because they are identical to each other, grows. Clonal evolution occurs like a tree with mutations causing many clones to branch off continuously.;

Details

Origin ID

C17609;

UMLS CUI

C0178874;

Automatic exact mappings (from CISMeF team)
- In progress (qualifier value) [SNOMED CT concept]
- Progress [LOINC component]
- Progress [ICNP judgement]
- Progressing to (qualifier value) [SNOMED CT concept]
- Progression (attribute) [SNOMED CT concept]
- Progressive [HPO term]
- Progressive (qualifier value) [SNOMED CT concept]
- progression [COVID-19 Thesaurus concept]
- progressive [SNOMED Notion]
- progressive [Radlex concept]
- transforming growth factor beta 1 [HGNC gene]
Currated CISMeF NLP mapping
- Neoplasm progression [MedDRA Preferred Term]
- Neoplasm progression NOS [MedDRA LLT]
- Tumor progression [MedDRA LLT]
- Tumor progression (finding) [SNOMED CT concept]
- Tumour progression [MedDRA LLT]
See also inter- (CISMeF)
- lesional progression [SYNODOS term]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Neoplasm progression [MedDRA Preferred Term]
- Neoplasm progression NOS [MedDRA LLT]
- Tumor progression [MedDRA LLT]
- Tumor progression (finding) [SNOMED CT concept]
- Tumour progression [MedDRA LLT]
biological_process_has_initiator_process
- Pathologic Process [NCIt concept]
biological_process_results_from_biological_process
- Cancer Cell Growth [NCIt concept]
concept_is_in_subset
- CPTAC Follow-Up Forms Terminology [NCIt concept]
- CPTAC Glioblastoma Multiforme Follow-Up Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
process_includes_biological_process
- Clonal Evolution [NCIt concept]
- Neovascularization [NCIt concept]
- Tumor Angiogenesis [NCIt concept]
process_involves_gene
- BCL7A Gene [NCIt concept]
- BCL7A wt Allele [NCIt concept]
- FRAT1 Gene [NCIt concept]
- FRAT1 wt Allele [NCIt concept]
- HULLK Gene [NCIt concept]
- HULLK wt Allele [NCIt concept]
- PRICKLE4 Gene [NCIt concept]
- PRICKLE4 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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