Preferred Label : COVID-19 Vaccine V591;
NCIt synonyms : SARS-CoV-2 Vaccine V591; MV-encoding SARS-CoV-2 Spike Protein Vaccine;
NCIt definition : A coronavirus vaccine based on a measles virus (MV) vector expressing the spike (S)
protein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), with
potential immunomodulating and anti-COVID-19 activities. Upon intramuscular administration
of the COVID-19 vaccine V591, the MV infects human cells, which produces SARS-CoV-2
S protein. The released S protein activates the immune system to induce a humoral
and cell-mediated immune response against SARS-CoV-2. This may prevent SARS-CoV-2
infection and inhibit viral replication. S protein, usually found on the surface of
SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;
Molecule name : V-591; TMV-083; V 591; TMV 083;
NCI Metathesaurus CUI : CL1413456;
Origin ID : C176056;
UMLS CUI : C5439914;
Semantic type(s)
- concept_is_in_subset
