Preferred Label : Proteasome Inhibitor TQB3602;
NCIt definition : An orally bioavailable proteasome inhibitor (PI) with potential antineoplastic activity.
Upon oral administration, proteasome inhibitor TQB3602 inhibits the activity of the
proteasome, blocking the targeted proteolysis normally performed by the proteasome,
which leads to an accumulation of unwanted or misfolded proteins, the disruption of
various cell signaling pathways, and resulting in the induction of apoptosis. Proteasomes
are large protease complexes that degrade unneeded or damaged proteins that have been
ubiquinated.;
Molecule name : TQB 3602; TQB-3602; TQB602;
NCI Metathesaurus CUI : CL1413424;
Origin ID : C175969;
UMLS CUI : C5446894;
Semantic type(s)
- concept_is_in_subset
