Preferred Label : Fluorine F 18-WL12;
NCIt synonyms : Fluorine F 18-labeled WL12; 18F-WL12; [18F]-WL12;
NCIt definition : A radiotracer composed of the programmed cell death-1 ligand 1 (PD-L1; cluster of
differentiation 274; CD274)-binding peptide WL12 radiolabeled with the radionuclide
fluorine F 18, with potential PD-L1 imaging activity using positron emission tomography
(PET). Upon administration of fluorine F 18-WL12, the WL12 moiety targets and binds
to PD-L1 expressed on certain tumor cells. Upon uptake and PET imaging, the radioisotope
moiety can be visualized and the extent of PD-L1 expression can be assessed. This
may be used to predict the therapeutic response to PD-L1-targeting agents.;
NCI Metathesaurus CUI : CL1413137;
Origin ID : C175948;
UMLS CUI : C5446876;
Semantic type(s)
- concept_is_in_subset
