Breast Tall Cell Carcinoma with Reversed Polarity

Preferred Label : Breast Tall Cell Carcinoma with Reversed Polarity;

NCIt synonyms : TCCRP;

NCIt definition : A rare subtype of invasive breast carcinoma characterized by tall columnar cells with reversed nuclear polarity, arranged in solid and solid papillary patterns, most commonly associated with IDH2 p.Arg172 hotspot mutations. (WHO 2019);

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1412922;

Details

Origin ID

C175607;

UMLS CUI

C5446657;

Currated CISMeF NLP mapping
- Tall cell carcinoma of breast with reversed polarity [ICD-11 More detail]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Breast Lump [NCIt concept]
- Pain [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Tall Columnar Adenocarcinoma Cell with Reversed Polarity [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
disease_may_have_molecular_abnormality
- IDH2 NP_002159.2:p.R172X [NCIt concept]

Keyword's position in hierarchy(ies) :

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