" /> Pentosan Polysulfate - CISMeF





Preferred Label : Pentosan Polysulfate;

NCIt synonyms : Xylan Polysulfate; Xylan Hydrogen Sulfate;

NCIt definition : A semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to relieve pain or discomfort associated with chronic inflammation of the bladder. It is also being evaluated for its protective effects on the gastrointestinal tract in people undergoing radiation therapy.;

UNII : F59P8B75R4;

CAS number : 39432-58-1; 37300-21-3;

Molecule name : CB-8061;

Chemical formula : (C5H8O10S2)n;

Codes from synonyms : CDR0000045294;

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28/05/2025


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