Preferred Label : Anti-SARS-CoV-2 Equine Immunoglobulin F(ab')2 Fragments INM005;
NCIt synonyms : Equine Hyperimmune Serum INM005;
NCIt related terms : INM-005;
NCIt definition : A preparation of equine hyperimmune immunoglobulin F(ab')2 fragments, generated from
antigenic stimulation with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV2)
receptor binding domain (RBD) protein, that can be used for passive immunization against
Coronavirus disease 2019 (COVID-19). Upon administration, the anti-SARS-CoV-2 equine
immunoglobulin F(ab')2 fragments INM005 specifically targets and binds to the RBD
of SARS-CoV-2 and may thereby neutralize the interaction of SARS-CoV-2 with its cellular
receptor. This may prevent the multiplication of the virus, slow the progression of
the disease and accelerate recovery, and may potentially provide temporary protection
against infection with SARS-CoV-2.;
UNII : QJ4WJD8DD3;
Molecule name : INM-005; INM 005;
NCI Metathesaurus CUI : CL1412610;
Origin ID : C175231;
UMLS CUI : C5418111;
Semantic type(s)
- concept_is_in_subset
