" /> Amubarvimab - CISMeF





Preferred Label : Amubarvimab;

NCIt synonyms : Anti-SARS-CoV-2 Spike Protein Monoclonal Antibody BRII-196; Monoclonal Antibody BRII-196; Anti-SARS-CoV-2 S Protein Monoclonal Antibody BRII-196;

NCIt definition : A neutralizing human monoclonal antibody, isolated from a patient who has recovered from the Coronavirus disease 2019 (COVID-19), directed against the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for passive immunization against COVID-19. Upon administration, amubarvimab specifically targets and binds to a highly conserved epitope on the SARS-CoV-2 S protein, thereby blocking viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may potentially provide temporary protection against infection with SARS-CoV-2. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

UNII : 2AD5KH3SE4;

CAS number : 2509447-07-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2509447-07-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BRII-196; BRII 196;

NCI Metathesaurus CUI : CL1412608;

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Keyword's position in hierarchy(ies) : arborescence

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21/05/2024


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