" /> Azeliragon - CISMeF





Preferred Label : Azeliragon;

NCIt definition : An orally bioavailable inhibitor of the receptor for advanced glycation end-products (RAGE), with potential antineoplastic activity. Upon oral administration, azeliragon targets and binds to RAGE, thereby preventing binding of RAGE ligands to RAGE, and prevents RAGE-mediated signaling, This may inhibit proliferation and induce apoptosis of tumor cells in which the RAGE pathway is overactivated. RAGE, a receptor belonging to the immunoglobulin superfamily, plays a key role in inflammation and is overexpressed in a variety of cancers. It plays a key role in tumor cell proliferation, survival and metastasis.;

UNII : LPU25F15UQ;

InChIKey : KJNNWYBAOPXVJY-UHFFFAOYSA-N;

CAS number : 603148-36-3;

Molecule name : TTP488; PF-04494700;

NCI Metathesaurus CUI : CL1412175;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
09/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.