Transplant-Associated Thrombotic Microangiopathy

Preferred Label : Transplant-Associated Thrombotic Microangiopathy;

NCIt synonyms : TA-TMA;

NCIt definition : Thrombotic microangiopathy that presents in some patients undergoing hematopoietic stem cell transplantation (HSCT). Though similar in presentation to thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS), transplant-associated thrombotic microangiopathy (TA-TMA) is a distinct disorder. Several risk factors may be associated with TA-TMA, including high-dose chemotherapy, radiation therapy, HLA mismatch, use of calcineurin inhibitors, acute graft-versus-host disease (GVHD), and infections.;

NCI Metathesaurus CUI : CL1411865;

Details

Origin ID

C174553;

UMLS CUI

C5417748;

Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Blood Vessel [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]

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