Preferred Label : Anti-SARS-CoV-2 Polyclonal Antibodies SAB-185;
NCIt synonyms : Tc Bovine-derived Anti-SARS-CoV-2 Human Immunoglobulin SAB-185;
NCIt related terms : SAB-185;
NCIt definition : A preparation of purified human immunoglobulin G (hIgG), neutralizing polyclonal antibodies
directed against the spike (S) protein of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) and derived from the plasma of immunized transchromosomic (Tc) bovines,
that can potentially be used for immunization and protection against Coronavirus disease
2019 (COVID-19). Upon administration of anti-SARS-CoV-2 polyclonal antibodies SAB-185,
the antibodies specifically target and bind to the SARS-CoV-2 S protein, thereby blocking
viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2.
This may slow the progression of the disease and accelerate recovery, and may potentially
provide temporary protection against infection with SARS-CoV-2. S protein, usually
found on the surface of SARS-CoV-2, plays an essential role in the infection pathway
of the SARS-CoV-2 virus.;
UNII : GZH7FFK82R;
Molecule name : SAB 185; SAB-185;
NCI Metathesaurus CUI : CL1411823;
Origin ID : C174542;
UMLS CUI : C5418105;
Semantic type(s)
- UMLS correspondences (same concept)
- SAB-185 [MeSH Supplementary Concept]
- concept_is_in_subset
