Aspirin/Dipyridamole

Preferred Label : Aspirin/Dipyridamole;

NCIt synonyms : Dipyridamole/Aspirin; Dipyridamole-Aspirin; Aspirin-Dipyridamole;

NCIt related terms : Aspirin and dipyridamole;

NCIt definition : A fixed combination of aspirin, a cyclooxygenase inhibitor, and dipyridamole, a phosphodiesterase (PDE) inhibitor, with antiplatelet and antithrombotic activities. Upon oral administration of aspirin/dipyridamole, aspirin binds to and irreversibly inhibits platelet cyclooxygenase, thereby inhibiting thromboxane A2 formation. This prevents platelet aggregation and vasoconstriction. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen.;

CAS number : 87653-67-6;

Drug name : Aggrenox;

NCI Metathesaurus CUI : CL1411819;

Codes from synonyms : 48;

Details

Origin ID

C174538;

UMLS CUI

C0732279;

Currated CISMeF NLP mapping
- Aspirin, Dipyridamole Drug Combination [MeSH Descriptor]
- aspirin, dipyridamole drug combination [MeSH concept]
See also inter- (CISMeF)
- Product containing aspirin and dipyridamole (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Aspirin, Dipyridamole Drug Combination [MeSH Descriptor]
- Product containing aspirin and dipyridamole (medicinal product) [SNOMED CT concept]
- aspirin, dipyridamole drug combination [MeSH concept]
concept_is_in_subset
- HemOnc Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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