Preferred Label : Flavonoid;
NCIt synonyms : Flavonols; 2-Phenyl-Chromene; 2-Phenyl-Benzopyran; 3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one;
NCIt related terms : Flavonol; 3-Hydroxyflavone;
NCIt definition : One of a number of chemical compounds found in certain fruits, vegetables and seeds
with antioxidant properties and potential antineoplastic properties. As polyphenolic,
soluble plant pigments, flavonoids are usually subdivided into 5 subgroups flavonols,
flavones, flavonones, flavan-3-ols, anthocyanidins. Although not considered essential
nutrients, some flavonoids may be beneficial to health by strengthening and protecting
blood vessels and connective tissue and acting as anti-inflammatory, antihistaminic,
and antiviral agents. As antioxidants, some flavonoids may protect lipids from oxidative
damage or retard the formation of cataracts. (NCI04);
Alternative definition : NCI-GLOSS: A member of a group of substances found in many plants and plant-based
foods. Flavonoids have shown antioxidant effects.; CRCH: A class of polyphenols which are biogenetically derived from a phenylpropane
(C6-C3 unit) and three C2 units to form a benzopyran with an additional phenyl group
at C-2 (C6-C3-C6 unit). They consist of 15 carbons and vary by oxidation/hydroxylation,
glycosidation, and other functional groups. Historically, the benzene ring is denoted
'A'-ring, the pyran ring 'C' ring, and the phenyl ring 'B'-ring. The numbering of
the phenyl ring starts with 1' (one prime) at the carbon that is connected to the
pyran ring, and follows along the phenyl ring with C-2', -3', -4', -5', and -6'.;
Unit used : mg;
NSC code : 57653;
ChEBI ID : CHEBI:47916; CHEBI:38672; CHEBI:63326;
Codes from synonyms : CDR0000330168; 30423; NSC0057653;
Origin ID : C1745;
UMLS CUI : C0596577;
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)