Preferred Label : Allogeneic Anti-CD20 CAR T-cells LUCAR-20S;
NCIt synonyms : LUCAR-20S CAR-T Cells;
NCIt definition : A preparation of donor-derived T-lymphocytes that have been genetically modified to
express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA)
CD20 (cluster of differentiation 20), with potential immunostimulating and antineoplastic
activities. Upon administration, allogeneic anti-CD20 CAR T-cells LUCAR-20S specifically
recognize and kill CD20-expressing tumor cells. The CD20 antigen, a non-glycosylated
cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in
B-cell lineage malignancies.;
Molecule name : LUCAR-20S; LUCAR 20S;
NCI Metathesaurus CUI : CL1411949;
Origin ID : C174397;
UMLS CUI : C5418084;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
