Preferred Label : Anti-HER2 Monoclonal Antibody B002;
NCIt definition : A humanized monoclonal antibody directed against the human epidermal growth factor
receptor 2 (HER2; ErbB2; HER-2), with potential antineoplastic activity. Upon administration,
anti-HER2 monoclonal antibody B002 targets and binds to HER2 on HER2-expressing tumor
cells. This prevents HER2-mediated signaling and may lead to antitumor activity. HER2,
a tyrosine kinase receptor, is overexpressed by many cancer cell types.;
Molecule name : B-002; B 002;
NCI Metathesaurus CUI : CL1407790;
Origin ID : C174121;
UMLS CUI : C5418066;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
