Aromatase Inhibitor

Preferred Label : Aromatase Inhibitor;

NCIt synonyms : Androstenedione Aromatase Inhibitor; Estrogen Synthetase Inhibitor; Estrogen Synthase Inhibitor;

NCIt related terms : Aromatase Inhibition Therapy;

NCIt definition : Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Inhibition of aromatase results in the suppression of estrogen-regulated processes.;

Alternative definition : NCI-GLOSS: A drug that prevents the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy for postmenopausal women who have hormone-dependent breast cancer.;

ChEBI ID : CHEBI:50790;

Codes from synonyms : CDR0000044232;

Details

Origin ID

C1740;

UMLS CUI

C0593802;

Automatic exact mappings (from CISMeF team)
- Aromatase inhibition therapy [MedDRA Preferred Term]
- Aromatase inhibitor (disposition) [SNOMED CT concept]
- Aromatase inhibitors [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Aromatase inhibitors [ATC Code]
- aromatase inhibitors [MeSH Descriptor]
- aromatase inhibitors [MeSH concept]
False automatic mappings
- Product containing aromatase inhibitor (product) [SNOMED CT concept]
- Substance with aromatase inhibitor mechanism of action (substance) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Aromatase inhibitors [ATC Code]
- Product containing aromatase inhibitor (product) [SNOMED CT concept]
- Substance with aromatase inhibitor mechanism of action (substance) [SNOMED CT concept]
- aromatase inhibitors [MeSH concept]
- aromatase inhibitors [MeSH Descriptor]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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