Preferred Label : Autologous Pancreatic Adenocarcinoma Lysate and mRNA-loaded Dendritic Cell Vaccine;
NCIt synonyms : Autologous Pancreatic Adenocarcinoma Lysate and mRNA-loaded Dendritic Cells; Autologous Pancreatic Adenocarcinoma Lysate and mRNA-loaded DCs; Autologous Pancreatic Adenocarcinoma Lysate and mRNA-loaded DC Vaccine;
NCIt definition : A cell-based cancer vaccine composed of autologous dendritic cells (DCs) loaded with
pancreatic adenocarcinoma lysate and mRNA containing and encoding tumor associated
antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon
administration by perinodal injection using ultrasound guidance, the autologous pancreatic
adenocarcinoma lysate and mRNA-loaded DC vaccine may stimulate an anti-tumoral cytotoxic
T-lymphocyte (CTL) response against tumor cells expressing the patient's tumor cell-specific
TAAs, which may result in tumor cell lysis.;
NCI Metathesaurus CUI : CL1407844;
Origin ID : C173968;
UMLS CUI : C5420489;
Semantic type(s)
- concept_is_in_subset
