Preferred Label : Protopine/Nuciferine Supplement;
NCIt synonyms : Protopine and Nuciferine Supplement; Protopine/Nuciferine;
NCIt definition : A nutritional supplement composed of the two alkaloids protopine, a benzylisoquinoline
alkaloid occurring in opium poppies and other plants of the Papaveraceae family, and
nuciferine, an alkaloid component of Nelumbo nucifera and Nymphaea caerulea, and in
certain plants of the Papaveraceae family, with antihistamine, anticholinergic, analgesic,
smooth muscle relaxing, central nervous system (CNS) suppressing and antipsychotic-like
activities. Upon administration, protopine inhibits histamine H1 receptors and exerts
opioid analgesic and sedative effects. As an antispasmodic, nuciferine relaxes smooth
muscle cells and prevents smooth muscle contractions. It also has a calming effect.
Together, protopine and nuciferine may relax the bladder and reduce urinary urgency
and frequency, thereby providing relief for urge incontinence. It may also ease bladder
pain and irritation.;
Drug name : Protoves M1;
NCI Metathesaurus CUI : CL1407849;
Origin ID : C173963;
UMLS CUI : C5420486;
Semantic type(s)
- Food [UMLS semantic type]
- concept_is_in_subset
