Activating KIT Gene Mutation

Preferred Label : Activating KIT Gene Mutation;

NCIt synonyms : Activating C-KIT Mutation; KIT Activating Mutation; Activating c-KIT Gene Mutation; Activating CD117 Gene Mutation; Activating v-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog Gene Mutation; Activating KIT Mutation; Activating KIT Proto-Oncogene Tyrosine Protein Kinase Gene Mutation;

NCIt definition : A change in the nucleotide sequence of the KIT gene that that results in constitutive activation of both mast/stem cell growth factor receptor Kit and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL1407688;

Details

Origin ID

C173887;

UMLS CUI

C5420430;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- KIT Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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