Preferred Label : Taniraleucel;
NCIt synonyms : Human Placental HSC-derived CD56 /CD3- NKs CYNK-001; Natural Killer Cells CYNK-001; Allogeneic Human Placental Hematopoietic Stem Cell Derived Natural Killer Cells CYNK-001; Allogeneic CD56 /CD3- Natural Killer Cells CYNK-001; Allogeneic CD56-positive CD3-negative Natural Killer Cells CYNK-001; CD56 /CD3- NK Cells CYNK-001; Cord Blood-derived Expanded NK Cells PNK-007; Cord Blood-derived Expanded Natural Killer Cells PNK-007; Human CB-derived Natural Killer Cells PNK-007;
NCIt definition : A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK)
cells derived from human placental hematopoietic stem cells (HSCs) and expressing
the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating,
antineoplastic and antiviral activities. Upon infusion of taniraleucel, these cells
are able to recognize tumor cells as well as virally-infected cells, secrete perforins,
granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells.;
UNII : XO25H8E4QP;
Molecule name : CYNK 001; CYNK-001; PNK-007; PNK 007;
NCI Metathesaurus CUI : CL1407641;
Origin ID : C173877;
UMLS CUI : C5848429;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
