Therapeutic Angiotensin II

Preferred Label : Therapeutic Angiotensin II;

NCIt related terms : ANGIOTENSIN II;

NCIt definition : A synthetic form of the endogenous angiotensin II, a peptide hormone of the renin-angiotensin-aldosterone system (RAAS) that causes vasoconstriction and an increase in blood pressure, that may be used for the treatment of septic or other distributive shock. Upon administration, therapeutic angiotensin II binds to angiotensin II type 1 receptor on vascular smooth muscle cells which leads to Ca2 /calmodulin-dependent phosphorylation of myosin. This causes smooth muscle contraction and results in vasoconstriction and an increase in blood pressure. Therapeutic angiotensin II also increases blood pressure by stimulating the release of the steroid hormone aldosterone, which regulates the renal absorption of water and sodium.;

UNII : M089EFU921;

CAS number : 4474-91-3;

NCI Metathesaurus CUI : CL1407728;

Details

Origin ID

C173802;

UMLS CUI

C5400662;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- angiotensin II [ATC Code]
Validated automatic mappings to NTBT
- Angiotensin II [LOINC component]
- Angiotensin II [MedDRA Preferred Term]
- Angiotensin II [SMS substance]
- Angiotensin II (substance) [SNOMED CT concept]
- angiotensin II [MeSH concept]
- angiotensin II [COVID-19 Thesaurus concept]
- angiotensin ii [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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