Preferred Label : Sclerosing Odontogenic Carcinoma;
NCIt synonyms : SOC;
NCIt definition : A rare, low-grade primary intraosseous carcinoma of the jaws, with bland cytology,
markedly sclerotic stroma, and aggressive infiltration. It is characterized by single-file
thin cords, nests, and strands of epithelium in a densely sclerotic stroma. Cytologically,
individual epithelial cells are bland, with infrequent mitoses. Their cytoplasm may
show vacuolation or partial clearing. There is no squamous differentiation. Despite
the benign appearance, there is invasion of skeletal muscle, and perineural infiltration
is characteristic. (WHO 2017);
Neoplastic status : Malignant;
NCI Metathesaurus CUI : CL1407547;
Origin ID : C173733;
UMLS CUI : C5401300;
Automatic exact mappings (from CISMeF team)
- Disease excludes abnormal cell
- Disease may have findings
- False automatic mappings
- Has associated anatomic sites
- Semantic type(s)
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
