Preferred Label : COVID-19 Vaccine Covax-19;
NCIt synonyms : SARS-CoV-2 Spike Protein Plus Adjuvant Advax-CpG55.2;
NCIt definition : A coronavirus vaccine composed of a recombinant form of the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) spike protein (SP) combined with a proprietary
polysaccharide-based vaccine adjuvant, Advax-CpG55.2, with potential immunomodulating
and anti-COVID-19 activities. Upon administration of Covax-19, the SARS-CoV-2 SP activates
the immune system to produce anti-SARS-CoV-2 SP antibodies and T-cell responses against
SARS-CoV-2 SP. The antibodies recognize the SP and kill SARS-CoV-2. This prevents
SARS-CoV-2 infection. SP, usually found on the surface of SARS-CoV-2, plays an essential
role in the infection pathway of the SARS-CoV-2 virus. The proprietary adjuvant strongly
stimulates both T-cell and antibody immune responses when combined with the recombinant
SARS-CoV-2 SP.;
Drug name : Covax-19;
NCI Metathesaurus CUI : CL1407553;
Origin ID : C173731;
UMLS CUI : C5420359;
Semantic type(s)
concept_is_in_subset