COVID-19 Vaccine Gam-COVID-Vac

Preferred Label : COVID-19 Vaccine Gam-COVID-Vac;

NCIt synonyms : rAd26/rAd5-expressing SARS-CoV-2 SP Vaccine Gam-COVID-Vac; Gam-COVID-Vac;

NCIt related terms : Sputnik V COVID-19 Vaccine;

NCIt definition : A recombinant human adenoviral (rAd)-based vaccine encoding for the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (SP), with potential immunomodulating and anti-COVID-19 activities. Gam-COVID-Vac contains two components: a rAd type 26 (rAd26) prime component encoding the SARS-CoV-2 S protein gene and a rAd type 5 (rAd5) boost component encoding the SARS-CoV-2 S protein gene. Upon intramuscular administration of the Gam-COVID-Vac, the Ad infects cells and produces SP. The released SP activates the immune system to induce a humoral and cell-mediated immune response against SARS-CoV-2. This may prevent SARS-CoV-2 infection and inhibit viral replication. SP, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

NCI Metathesaurus CUI : CL1407551;

Details

Origin ID

C173729;

UMLS CUI

C5400622;

Automatic exact mappings (from CISMeF team)
- Gam-COVID-Vac [COVID-19 Thesaurus concept]
- Gam-COVID-Vac vaccine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Gam-COVID-Vac vaccine [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- SeroNet Authorized Values [NCIt concept]
- SeroNet Study Descriptors [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients