" /> Recombinant 2019-nCoV S Protein Subunit-trimer Vaccine SCB-2019 - CISMeF





Preferred Label : Recombinant 2019-nCoV S Protein Subunit-trimer Vaccine SCB-2019;

NCIt synonyms : Recombinant SARS-CoV-2 Trimeric S Protein Subunit Vaccine SCB-2019; Recombinant S-trimer Subunit Vaccine SCB-2019; COVID-19 Vaccine SCB-2019 (SY); S-Trimer COVID-19 Vaccine SCB-2019;

NCIt definition : A covalently-trimerized fusion protein-based vaccine composed of a C-prodomain peptide of human collagen covalently bound to the viral spike protein (SP) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), thereby resembling the native trimeric viral SP, with potential immunomodulating and anti-COVID-19 activities. Upon intramuscular administration of the recombinant 2019-nCoV S protein subunit-trimer vaccine SCB-2019, the SP activates the immune system to create anti-SARS-CoV-2 SP antibodies. The antibodies recognize and neutralize the SP and kill SARS-CoV-2. This prevents SARS-CoV-2 infection. SP, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

Molecule name : SCB-2019; SCB 2019;

NCI Metathesaurus CUI : CL1407550;

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Keyword's position in hierarchy(ies) : arborescence

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22/05/2024


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