TAX Gene - CISMeF

Preferred Label : TAX Gene;

NCIt definition : The genes coding for the Trans-Activator X (tax) protein of HTLV-I and II. Tax activates transcription via interactions with the ATF/CREB transactivator(s) and the CBP/p300 coactivators which assemble as a multiprotein complex on the 21-bp repeat elements in the proviral LTR. Tax also modulates expression of cellular genes via the ATF/CREB and NF-kappaB pathways.;

Details

Origin ID

C17363;

UMLS CUI

C0079428;

Automatic exact mappings (from CISMeF team)
- genes, px [MeSH Descriptor]
Currated CISMeF NLP mapping
- tax genes [MeSH concept]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- tax genes [MeSH concept]
gene_found_in_organism
- Human Immunodeficiency Virus [NCIt concept]
gene_plays_role_in_process
- Transcriptional Activation [NCIt concept]
- Viral Function [NCIt concept]

Keyword's position in hierarchy(ies) :

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