Advanced Gastrointestinal Stromal Tumor

Preferred Label : Advanced Gastrointestinal Stromal Tumor;

NCIt synonyms : Advanced GIST;

NCIt definition : A gastrointestinal stromal tumor that has spread extensively to other anatomic sites or is no longer responding to treatment.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1407468;

Details

Origin ID

C173502;

UMLS CUI

C5420237;

Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Disease may have findings
- Lesion with Diameter Greater than 10 cm [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Intermediate Filaments Present [NCIt concept]
- Intracytoplasmic Eosinophilic Inclusion [NCIt concept]
- Localized Disease [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
disease_has_finding
- Extensive Stage Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Metastatic Lesion [NCIt concept]
- More than 5 Mitoses per 50 HPF [NCIt concept]
- Secondary Lesion [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Interstitial Cell of Cajal [NCIt concept]
- Stromal Cell [NCIt concept]
disease_has_normal_tissue_origin
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_mapped_to_gene
- KIT Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 14 [NCIt concept]
- Loss of Chromosome 1p [NCIt concept]
- Loss of Chromosome 22 [NCIt concept]
disease_may_have_molecular_abnormality
- KIT Gene Mutation [NCIt concept]
- PDGFRA Gene Mutation [NCIt concept]

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