Activating KRAS Exon 4 Mutation

Preferred Label : Activating KRAS Exon 4 Mutation;

NCIt synonyms : Activating KRAS2 Exon 4 Mutation; Activating KRAS-2 Exon 4 Mutation; Activating KRAS Exon 4 Gene Mutation; Activating v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog Exon 4 Mutation; KRAS Exon 4 Activating Gene Mutation; KRAS Exon 4 Activating Mutation; Activating c-K-ras Exon 4 Mutation;

NCIt definition : A change in the nucleotide sequence of exon 4 of the KRAS gene that results in constitutive activation of both GTPase KRas protein and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL1407420;

Details

Origin ID

C173445;

UMLS CUI

C5420204;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- KRAS Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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