Preferred Label : Autologous Monocyte-derived Lysate-pulsed Dendritic Cell Vaccine PV-001-DC;
NCIt synonyms : Autologous Monocyte-derived Lysate Pulsed DCs PV-001-DC; Autologous Monocyte-derived Lysate-pulsed Dendritic Cells PV-001-DC; PV-001-Dendritic Cell;
NCIt definition : A cell-based cancer vaccine composed of autologous, monocyte-derived dendritic cells
(mDCs) pulsed with tumor cell lysate containing tumor associated antigens (TAAs),
with potential immunostimulatory and antineoplastic activities. Upon administration,the
autologous tumor cell lysate-pulsed mDCs vaccine PV-001-DC may stimulate an anti-tumoral
cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the patient's
tumor cell-specific TAAs, which may result in tumor cell lysis.;
Molecule name : PV-001-DC;
NCI Metathesaurus CUI : CL1407425;
Origin ID : C173442;
UMLS CUI : C5417986;
Semantic type(s)
- concept_is_in_subset
