Cutaneous Merkel Cell Carcinoma

Preferred Label : Cutaneous Merkel Cell Carcinoma;

NCIt synonyms : Cutaneous Neuroendocrine Carcinoma; Neuroendocrine Carcinoma of Skin; Skin Neuroendocrine Carcinoma; Skin Merkel Cell Carcinoma; Trabecular Skin Carcinoma; Neuroendocrine Carcinoma of the Skin;

NCIt related terms : trabecular cancer;

NCIt definition : A rare aggressive neuroendocrine carcinoma that arises from the skin and most often affects older individuals. It is usually located in the head, neck, and extremities. The tumor is composed of small round cells with scanty cytoplasm. Merkel cell polyomavirus is implicated in the majority of cases.;

Alternative definition : NCI-GLOSS: A rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been exposed to the sun. It is most common in older people and in people with weakened immune systems.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1407234;

Codes from synonyms : CDR0000579914; CDR0000386222;

Details

Origin ID

C173385;

UMLS CUI

C5420179;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Head and Neck [NCIt concept]
- Lung [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Intermediate Grade Neuroendocrine Lesion [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Malignant Neuroendocrine Small Round Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Cytoplasmic Membrane-Bound Granules Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Single Cell Necrosis [NCIt concept]
- Trabecular Pattern [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]
disease_may_have_associated_disease
- Merkel Cell Polyomavirus Infection [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 6 [NCIt concept]
- del(1p36) [NCIt concept]

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