Preferred Label : Pidacmeran;
NCIt synonyms : BNT162c2 COVID-19 Vaccine; BNT1162c2 SARS-CoV-2 Vaccine;
NCIt definition : A formulation consisting of lipid nanoparticle (LNP) encapsulating a specific form
of messenger RNA encoding the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
spike glycoprotein (SP), with potential immunizing and anti-COVID-19 activities. Upon
injection of pidacmeran, the LNPs bind to the plasma membrane of nearby cells and
release SARS-CoV-2 SP mRNA into the cell. The mRNA is then translated by the cellular
protein translation machinery to produce SARS-CoV-2 SP. This may stimulate the immune
system to induce an antibody and T-cell-mediated immune response. This may provide
active immunization against SARS-CoV-2 infection. SP, usually found on the surface
of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2
virus.;
UNII : 6FH8H9CL41;
CAS number : 2417904-10-8;
Molecule name : BNT-162c2; BNT 162c2;
NCI Metathesaurus CUI : CL1406828;
Origin ID : C173056;
UMLS CUI : C5432267;
Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
