Ad5-nCoV COVID-19 Vaccine

Preferred Label : Ad5-nCoV COVID-19 Vaccine;

NCIt synonyms : Adenovirus Type 5-encoding SARS-CoV-2 Spike Protein; Ad5-encoding SARS-CoV-2 Spike Protein Vaccine; Ad5-nCoV COVID-19;

NCIt definition : A recombinant, replication-deficient coronavirus vaccine composed of a genetically engineered adenovirus type 5 (Ad5) vector that expresses full-length SARS-CoV-2 spike protein (SP), with potential immunomodulating and anti-COVID-19 activities. Upon intramuscular administration of the Ad5-nCoV vaccine, the Ad5 infects human cells, which produce the SARS-CoV-2 SP, and travel to the lymph nodes where the immune system creates anti-SARS-CoV-2 SP antibodies. The antibodies recognize the SP and kill SARS-CoV-2. This prevents SARS-CoV-2 infection. SP, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

NCI Metathesaurus CUI : CL1406788;

Details

Origin ID

C173017;

UMLS CUI

C5419987;

Automatic exact mappings (from CISMeF team)
- Ad5-nCoV vaccine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ad5-nCoV vaccine [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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