Covid-19 aAPC Vaccine

Preferred Label : Covid-19 aAPC Vaccine;

NCIt synonyms : Covid-19/aAPC Vaccine; Covid-19 Artificial Antigen Presenting Cell Vaccine;

NCIt definition : A vaccine composed of artificial antigen presenting cells (aAPCs) that have been lentivirally transduced with synthetic minigenes that have been engineered based on conserved domains of selected severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) viral structural proteins and immune modulatory genes, with potential immunizing and anti-viral activities. Upon subcutaneous administration of the Covid-19 aAPC vaccine, the viral proteins and immune modulatory genes are expressed and may activate the immune system to elicit a specific cytotoxic T-cell (CTL) response against the SARS-CoV-2 viral antigens encoded by the minigenes.;

NCI Metathesaurus CUI : CL1406785;

Details

Origin ID

C173012;

UMLS CUI

C5419986;

Automatic exact mappings (from CISMeF team)
- Covid-19 aAPC vaccine [MeSH concept]
- Covid-19 aAPC vaccine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Covid-19 aAPC vaccine [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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