Preferred Label : Alextatug;
NCIt synonyms : Anti-RNP Antibody ATRC-101; Anti-Ribonucleoprotein Antibody ATRC-101;
NCIt definition : An engineered, human immunoglobulin (Ig) G1 monoclonal antibody directed against a
ribonucleoprotein (RNP) complex, with potential immunostimulating and antineoplastic
activities. Upon administration, alextatug targets and binds to its RNP complex antigen
on tumor cells. This may activate the innate immune system, change the local tumor
microenvironment (TME) and promote T cell-mediated killing of tumor cells. The tumor-restricted
RNP complex is expressed in a variety of tumor cells.;
UNII : LF64CQ4EC6;
CAS number : 2768264-93-1;
Molecule name : ATRC 101; ATRC-101;
NCI Metathesaurus CUI : CL1406946;
Origin ID : C172924;
UMLS CUI : C5417949;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
