Preferred Label : Ursolic Acid;
NCIt synonyms : (3beta)-3-Hydroxyurs-12-en-28-oic Acid;
NCIt definition : A pentacyclic triterpenoid found in various fruits, vegetables and medicinal herbs,
with a variety of potential pharmacologic activities including anti-inflammatory,
antioxidative, antiviral, serum lipid-lowering, and antineoplastic activities. Upon
administration, ursolic acid may promote apoptosis and inhibit cancer cell proliferation
through multiple mechanisms. This may include the regulation of mitochondrial function
through various pathways including the ROCK/PTEN and p53 pathways, the suppression
of the nuclear factor-kappa B (NF-kB) pathways, and the increase in caspase-3, caspase-8
and caspase-9 activities.;
UNII : P3M2575F3F;
InChIKey : WCGUUGGRBIKTOS-GPOJBZKASA-N;
CAS number : 77-52-1;
NCI Metathesaurus CUI : CL1406899;
Origin ID : C172843;
UMLS CUI : C0077938;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
