Chromogranin-A

Preferred Label : Chromogranin-A;

NCIt synonyms : Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; CHGA; CgA; SP-I; Chromogranin A; PSP; Secretory Protein I;

NCIt definition : Chromogranin-A (457 aa, 51 kDa) is encoded by the human CHGA gene. This protein plays a role in the modulation of both blood pressure and pancreatic release of insulin.;

NCIt note : Chromogranin-A is a precursor that is cleaved to produce more than 20 biologically active peptides including: vasostatin-1, vasostatin-2, EA-92, ES-43, pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, catestatin (SL21), GV-19, GR-44, ER-37, GE-25, parastatin, chromofungin, chromostatin (CST), serpinin-RRG, serpinin and p-Glu serpenin precursor.;

Details

Origin ID

C17284;

UMLS CUI

C1609756;

Currated CISMeF NLP mapping
- Chromogranin (substance) [SNOMED CT concept]
- Chromogranin A [LOINC component]
- chromogranin A [MeSH concept]
- chromogranin A (344-358) [MeSH concept]
- chromogranin a [MeSH Descriptor]
- chromogranin a [SNOMED Notion]
- chromogranins [MeSH concept]
- chromogranins [MeSH Descriptor]
False automatic mappings
- Chromogranin A (substance) [SNOMED CT concept]
- chromogranin A (1-40) [MeSH concept]
- chromogranin A (1-40) [MeSH Supplementary Concept]
- chromogranin A (1-78) [MeSH concept]
- chromogranin A (1-78) [MeSH Supplementary Concept]
- chromogranin A (16-40) [MeSH concept]
- chromogranin A (16-40) [MeSH Supplementary Concept]
- chromogranin A (173-194) [MeSH concept]
- chromogranin A (173-194) [MeSH Supplementary Concept]
- chromogranin A (344-358) [MeSH Supplementary Concept]
- chromogranin A (344-364) [MeSH concept]
- chromogranin A (344-364) [MeSH Supplementary Concept]
- chromogranin A (347-419) [MeSH concept]
- chromogranin A (367-391) [MeSH concept]
- chromogranin A (367-391) [MeSH Supplementary Concept]
- chromogranin A (4-16) [MeSH concept]
- chromogranin A (4-16) [MeSH Supplementary Concept]
- chromogranin A (7-57) [MeSH concept]
- chromogranin A (7-57) [MeSH Supplementary Concept]
OMIM relation
- Chromogranin a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CHGA protein, human [MeSH Supplementary Concept]
- CHGA protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CHGA Gene [NCIt concept]
- Chromogranin Gene [NCIt concept]
- Peptide Hormone Gene [NCIt concept]
gene_product_has_associated_anatomy
- Adrenal Medulla [NCIt concept]
- Monocyte [NCIt concept]
- Neutrophil [NCIt concept]
- Pancreas [NCIt concept]
- Secretory Granule [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_is_biomarker_of
- Neuroendocrine Carcinoma [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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