" /> Molnupiravir - CISMeF





Preferred Label : Molnupiravir;

NCIt synonyms : Uridine, 4-Oxime, 5'-(2-Methylpropanoate); N4-Hydroxycytidine, 5'-Isopropyl Ester;

NCIt related terms : SARS-CoV-2 antiviral agents: molnupiravir;

NCIt definition : An orally bioavailable prodrug of EIDD-1931, the synthetic ribonucleoside derivative N4-hydroxycytidine and ribonucleoside analog, with potential antiviral activity against a variety of RNA viruses. Upon oral administration, molnupiravir, being a prodrug, is metabolized into its active form EIDD-1931 and converted into its triphosphate (TP) form. The TP form of EIDD-1931 is incorporated into RNA and inhibits the action of viral RNA-dependent RNA polymerase. This results in the termination of RNA transcription and decreases viral RNA production, and viral RNA replication.;

UNII : YA84KI1VEW;

InChIKey : HTNPEHXGEKVIHG-QCNRFFRDSA-N;

CAS number : 2349386-89-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2349386-89-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Lagevrio;

Molecule name : EIDD-2801; EIDD 2801; MK-4482; MK 4482;

NCI Metathesaurus CUI : CL1406746;

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Keyword's position in hierarchy(ies) : arborescence

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21/05/2024


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