Preferred Label : Severe Acute Respiratory Distress Syndrome;
NCIt synonyms : Severe ARDS;
NCIt definition : A form of acute respiratory distress syndrome (ARDS) that is marked by severe hypoxemia.
Based on the Berlin criteria, onset must occur within one week of a clinical insult
or there must be evidence of new or worsening respiratory symptoms. Chest imaging
reveals bilateral opacities consistent with pulmonary edema that are not fully explained
by effusions, lobar/lung collapse, or nodules. Respiratory failure is not fully explained
by heart failure or fluid overload and objective assessment, e.g. echocardiography,
is required to exclude hydrostatic edema if no risk factor is present. Additionally,
oxygenation as measured by a partial pressure of arterial oxygen (PaO2) to the fraction
of inspired oxygen (FIO2) is equivalent to 100 mm Hg or less with positive end-expiratory
pressure (PEEP) of at least 5 cm of water (Ranieri VM et al., JAMA. 2012;307(23):2526-2533).
Severe ARDS may be associated with cytokine release syndrome.;
NCI Metathesaurus CUI : CL1406505;
Origin ID : C172378;
UMLS CUI : C5419624;
Semantic type(s)
- concept_is_in_subset
