Preferred Label : Conditionally Reprogrammed Cells;
NCIt synonyms : Classical CRC; CRC; Classical Conditionally Reprogrammed Cells; 2D Classical Conditionally Reprogrammed Cells;
NCIt definition : A cellular sample derived from epithelial cells isolated from a tissue sample that
were rapidly expanded in a monolayer culture in the presence of irradiated mouse cells
and a Rho kinase (ROCK) inhibitor. Under these conditions the cells are reprogrammed
to be more stem-like but the reprogramming is conditional. When the cells are transferred
to cultures that mimic in vivo environments they become differentiated and can form
structures that resemble the tissue from which they were derived.;
NCI Metathesaurus CUI : CL1406128;
PubMed : 23169653;
Origin ID : C172257;
UMLS CUI : C5401389;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
