Preferred Label : Larotinib Mesylate;
NCIt definition : The mesylate salt form of larotinib, a reversible pan-ErbB inhibitor with potential
antineoplastic activity. Upon administration, larotinib binds to and inhibits ErbB
tyrosine receptor kinases, which may result in the inhibition of cellular proliferation
and angiogenesis in tumors expressing ErbB. The ErbB protein family, also called the
epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation
and tumor vascularization.;
Molecule name : Z-650; Z 650;
NCI Metathesaurus CUI : CL1406186;
Origin ID : C172062;
UMLS CUI : C5419439;
Semantic type(s)
- concept_is_in_subset
