" /> PEG Recombinant Human Megakaryocyte Growth and Development Factor - CISMeF





Preferred Label : PEG Recombinant Human Megakaryocyte Growth and Development Factor;

NCIt synonyms : Polyethylene Glycosylated Recombinant Human MGDF; PEG-MGDF; Pegylated Recombinant Human Megakaryocyte Growth and Development Factor; PEG-rHuMGDF; PEG-Thrombopoietin; Polyethylene Glycol-Recombinant Human Megakaryocyte Growth and Development Factor;

NCIt related terms : polyethylene glycosylated recombinant human megakaryocyte growth and development factor; PEG-rhMGDF;

NCIt definition : A pegylated formulation containing a recombinant growth factor with thrombopoietic activity. The recombinant human megakaryocyte growth and development factor (rHuMGDF) component of this formulation is a nonglycosylated, truncated form of the Mpl ligand. Mpl ligand, also known as thrombopoietin, stimulates the production of megakaryocyte precursor cells, megakaryocytes, and mature platelets. rHuMGDF is complexed with polyethylene glycol to prolong its half life in vivo and is used for the treatment and prevention of thrombocytopenia.;

Alternative definition : NCI-GLOSS: A form of megakaryocyte growth and development factor (MGDF) that is made in the laboratory. MGDF comes from the protein thrombopoietin, which is normally made in the body to help make platelets. PEG-rhMGDF is being studied as a way to increase the number of platelets in patients receiving chemotherapy.;

Drug name : Megagen;

Codes from synonyms : CDR0000413728; CDR0000413729; CDR0000045822;

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08/05/2025


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