Batoclimab - CISMeF

Preferred Label : Batoclimab;

NCIt definition : A human monoclonal antibody directed against the neonatal crystallizable fragment receptor (FcRn), with potential immunomodulating activity. Upon administration, batoclimab targets and binds to FcRn at the immunoglobulin G (IgG) binding site, thereby preventing the interaction between FcRn and the serum protein IgG. By preventing FcRn/IgG binding, batoclimab blocks the FcRn-mediated rescue of IgG, enables IgG degradation and prevents IgG-mediated inflammation. IgG plays a key role in many autoimmune diseases and is an important factor in inflammatory processes.;

UNII : C98V9UMX3D;

CAS number : 2187430-05-1;

Molecule name : HBM 9161; HL-161; HL 161; HBM-9161;

NCI Metathesaurus CUI : CL1406017;

Details

Origin ID

C171826;

UMLS CUI

C5419322;

Currated CISMeF NLP mapping
- Batoclimab [SMS substance]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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